Descripción del título
Basic aspects of catechol-O...
"Since its discovery in 1958, the Catechol-O-methyltransferase (COMT) enzyme has generated a lot of excitement, particularly so in more recent years with the discovery of clinically relevant COMT inhibitors in the late 1980's. While the volume of published research on the COMT enzyme and its inhibitors is substantial, there is no comprehensive, up-to-date source containing all the information available on basic COMT biochemistry and pharmacology, as well as critical review of results from clinical trials. This volume of International Review of Neurobiology summarizes what is currently known about COMT enzyme: its genomics, structure, function and biochemical properties; and presents up-to-date evaluation of the clinical use of COMT inhibitors as an adjunct to levodopa/dopa decarboxylase inhibitor treatment in Parkinson's disease."--Publisher's description
Monografía
monografia Rebiun16056467 https://catalogo.rebiun.org/rebiun/record/Rebiun16056467 m o d cr cnu---unuuu 110216s2010 ne ob 001 0 eng d 9780123813275 0123813271 9780123813268 0123813263 N. eng. N. QCL. CDX. UKMGB. OCLCQ. OPELS. OCLCQ. YDXCP. OPELS. OCLCF. UNAV Basic aspects of catechol-O-methyltransferase and the clinical applications of its inhibitors Recurso electrónico] edited by Erkki Nissinen Amsterdam Boston Elsevier/Academic Press 2010 Amsterdam Boston Amsterdam Boston Elsevier/Academic Press 1 recurso electrónico (xii, 323 p.) 1 recurso electrónico (xii, 323 p.) International review of neurobiology 95 Science Direct e-books Incluye referencias bibliográficas e índice "Since its discovery in 1958, the Catechol-O-methyltransferase (COMT) enzyme has generated a lot of excitement, particularly so in more recent years with the discovery of clinically relevant COMT inhibitors in the late 1980's. While the volume of published research on the COMT enzyme and its inhibitors is substantial, there is no comprehensive, up-to-date source containing all the information available on basic COMT biochemistry and pharmacology, as well as critical review of results from clinical trials. This volume of International Review of Neurobiology summarizes what is currently known about COMT enzyme: its genomics, structure, function and biochemical properties; and presents up-to-date evaluation of the clinical use of COMT inhibitors as an adjunct to levodopa/dopa decarboxylase inhibitor treatment in Parkinson's disease."--Publisher's description Nissinen, Erkki