Descripción del título
This volume gathers the latest exciting findings on ADP-ribosylation from renowned experts in the field. It includes ten chapters, organized into the following three thematic sections: Evolution and detection of endogenous ADP-ribosylation ADP-ribosylation by the ARTC family of ADP-ribosyltransferases (R-S-E ARTs) ADP-ribosylation by the ARTD family of ADP-ribosyltransferases (H-Y-E ARTs) The book will provide readers a better understanding of ADP-ribosylating toxins and their endogenous relatives. This provides a basis for developing novel toxin-neutralizing drugs and drugs targeting endogenous ADP-ribosyltransferase relatives
Monografía
monografia Rebiun17547222 https://catalogo.rebiun.org/rebiun/record/Rebiun17547222 141024s2015 gw | s |||| 0|eng d 9783319107714 978-3-319-10771-4 9783319107707 10.1007/978-3-319-10771-4. doi UPNA0452016 UMA.RE Endogenous ADP-Ribosylation Recurso electrónico] edited by Friedrich Koch-Nolte Servicio en línea New York [etc.] Springer New York [etc.] New York [etc.] Springer VIII, 213 p VIII, 213 p Current Topics in Microbiology and Immunology 0070-217X 384 The natural history of ADP-ribosyltransferases and the ADP ribosylation system -- Identification and Analysis of ADP-ribosylated Proteins -- Photorhabdus luminescens toxins TccC3 and TccC5: Insecticidal ADP-ribosyltransferases that modify threonine and glutamine -- Reaction mechanism of mono-ADP-ribosyltransferase based on structures of the complex of enzyme and substrate protein -- Regulation of nitrogenase by reversible mono-ADP-ribosylation -- ADP-ribosylation of P2X7: a matter of life and death for regulatory T cells and natural killer T cells -- Pierisins and CARP-1: ADP-ribosylation of DNA by ARTCs in butterflies and shellfish -- Comparative structural analysis of the putative mono-ADP-ribosyltransferases of the ARTD/PARP family -- Function and regulation of the mono-ADP-ribosyltransferase ARTD10 -- Regulation of nucleocytoplasmic transport by ADP-ribosylation: the emerging role of karyopherin-1 mono-ADP-ribosylation by ARTD15 This volume gathers the latest exciting findings on ADP-ribosylation from renowned experts in the field. It includes ten chapters, organized into the following three thematic sections: Evolution and detection of endogenous ADP-ribosylation ADP-ribosylation by the ARTC family of ADP-ribosyltransferases (R-S-E ARTs) ADP-ribosylation by the ARTD family of ADP-ribosyltransferases (H-Y-E ARTs) The book will provide readers a better understanding of ADP-ribosylating toxins and their endogenous relatives. This provides a basis for developing novel toxin-neutralizing drugs and drugs targeting endogenous ADP-ribosyltransferase relatives Modo de acceso: Word Wide Web Modo de acceso: World Wide Web Springer (e-Books) Medicine Immunology Medical microbiology Pharmacology Biomedicine Pharmacology/Toxicology Medical Microbiology Immunology Koch-Nolte, Friedrich SpringerLink Books (Servicio en línea) Current Topics in Microbiology and Immunology 0070-217X 384