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Modeling Phase Transitions ...
Foreword by Walter J. Freeman. The induction of unconsciousness using anesthetic drugs demonstrates that the cerebral cortex can operate in two very different modes: alert and responsive versus unaware and quiescent. But the states of wakefulness and sleep are not single-neuron properties---they emerge as bulk properties of cooperating populations of neurons, with the switchover between states being similar to the physical change of phase observed when water freezes or ice melts. Some brain-state transitions, such as sleep cycling, anesthetic induction, epileptic seizure, are obvious and detected readily with a few EEG electrodes; others, such as the emergence of gamma rhythms during cognition, or the ultra-slow BOLD rhythms of relaxed free-association, are much more subtle. The unifying theme of this book is the notion that all of these bulk changes in brain behavior can be treated as phase transitions between distinct brain states. "Modeling Phase Transitions in the Brain" contains chapter contributions from leading researchers who apply state-space methods, network models, and biophysically-motivated continuum approaches to investigate a range of neuroscientifically relevant problems that include analysis of nonstationary EEG time-series; network topologies that limit epileptic spreading; saddle--node bifurcations for anesthesia, sleep-cycling, and the wake--sleep switch; prediction of dynamical and noise-induced spatiotemporal instabilities underlying BOLD, alpha-, and gamma-band EEG oscillations, gap-junction-moderated Turing structures, and Hopf--Turing interactions leading to cortical waves. Written for: Researchers, clinicians, physicians, neurologists About the editors: Alistair Steyn-Ross and Moira Steyn-Ross are computational and theoretical physicists in the Department of Engineering, University of Waikato, New Zealand. They share a long-standing interest in the application of physics-based methods to gain insight into the emergent behavior of complex biological systems such as single neurons and interacting neural populations
Monografía
monografia Rebiun17226808 https://catalogo.rebiun.org/rebiun/record/Rebiun17226808 cr nn 008mamaa 100316s2010 xxu| s |||| 0|eng d 9781441907967 978-1-4419-0796-7 10.1007/978-1-4419-0796-7 doi UPVA 996882013803706 UAM 991007699474404211 CBUC 991010405312806709 CBUC 991015836159706706 UR0321900 PSAN bicssc MED057000 bisacsh 612.8 23 Steyn-Ross, D. Alistair Modeling Phase Transitions in the Brain Recurso electrónico-En línea] edited by D. Alistair Steyn-Ross, Moira Steyn-Ross New York, NY Springer New York 2010 New York, NY New York, NY Springer New York XXV, 350p. 103 illus., 24 illus. in color. digital XXV, 350p. 103 illus., 24 illus. in color. Springer Series in Computational Neuroscience 4 Biomedical and Life Sciences (Springer-11642) Accesible sólo para usuarios de la UPV Recurso a texto completo Foreword by Walter J. Freeman. The induction of unconsciousness using anesthetic drugs demonstrates that the cerebral cortex can operate in two very different modes: alert and responsive versus unaware and quiescent. But the states of wakefulness and sleep are not single-neuron properties---they emerge as bulk properties of cooperating populations of neurons, with the switchover between states being similar to the physical change of phase observed when water freezes or ice melts. Some brain-state transitions, such as sleep cycling, anesthetic induction, epileptic seizure, are obvious and detected readily with a few EEG electrodes; others, such as the emergence of gamma rhythms during cognition, or the ultra-slow BOLD rhythms of relaxed free-association, are much more subtle. The unifying theme of this book is the notion that all of these bulk changes in brain behavior can be treated as phase transitions between distinct brain states. "Modeling Phase Transitions in the Brain" contains chapter contributions from leading researchers who apply state-space methods, network models, and biophysically-motivated continuum approaches to investigate a range of neuroscientifically relevant problems that include analysis of nonstationary EEG time-series; network topologies that limit epileptic spreading; saddle--node bifurcations for anesthesia, sleep-cycling, and the wake--sleep switch; prediction of dynamical and noise-induced spatiotemporal instabilities underlying BOLD, alpha-, and gamma-band EEG oscillations, gap-junction-moderated Turing structures, and Hopf--Turing interactions leading to cortical waves. Written for: Researchers, clinicians, physicians, neurologists About the editors: Alistair Steyn-Ross and Moira Steyn-Ross are computational and theoretical physicists in the Department of Engineering, University of Waikato, New Zealand. They share a long-standing interest in the application of physics-based methods to gain insight into the emergent behavior of complex biological systems such as single neurons and interacting neural populations Reproducción electrónica Forma de acceso: Web Medicine Neurosciences Anesthesiology Neurology Biology-Data processing Neurobiology Biomedicine Neurosciences Anesthesiology Neurology Computer Appl. in Life Sciences Neurobiology Steyn-Ross, Moira SpringerLink (Servicio en línea) Springer eBooks Springer eBooks Printed edition 9781441907950 Springer Series in Computational Neuroscience 4