Descripción del título
Actin is one of the most abundant proteins and ubiquitously expressed in all eukaryotes. In recent years, the analysis of structure and function of such complexes has shed new light on actin's role in cellular and tissue morphogenesis, locomotion and various forms of intracellular motility, but also on its role in nuclear processes like chromatin architecture and transcription. Progress in understanding these different physiological phenomena, but also in unravelling the basis of actin-based pathophysiological processes has been made by combining video microscopy, molecular biology, genetics and biochemistry. Thus, the current research on actin, as ongoing in many international laboratories, is a "hot spot" in basic and translational research in life sciences. In this book on "The Actin Cytoskeleton", twelve internationally renowned authors present specific chapters that cover their recent work concerned with the various roles of actin mentioned above. This comprehensive volume is therefore an attractive handbook for teachers and students in many fields of medicine and pharmacology
Monografía
monografia Rebiun18708419 https://catalogo.rebiun.org/rebiun/record/Rebiun18708419 cr c||||||||| 170103s2017 gw o 001 0 eng d 9783319463711 978-3-319-46371-1 10.1007/978-3-319-46371-1 doi CBUC 991050720379706706 UPVA 996876112203706 UAM 991007668053704211 UR0408123 UAL spa UAL rdc 615 23 The Actin Cytoskeleton edited by Brigitte M Jockusch Cham Springer International Publishing Imprint: Springer 2017 Cham Cham Springer International Publishing Imprint: Springer 1 recurso en línea 1 recurso en línea XII, 352 p. 60 il., 30 il. en color XII, 352 p. 60 il., 30 il. en color Texto (visual) isbdcontent electrónico isbdmedia Springer eBooks Handbook of Experimental Pharmacology 0171-2004 235 Functional significance of actin isoforms -- Assembly and maintenance of myofibrils in striated muscle cells -- Myosins: Domain organisation, motor properties, physiological roles and cellular functions -- Actin filament structures in migrating vertebrate cells -- Signalling pathways controlling cellular actin organization -- Actin-based endocytosis -- ADP-ribosylation and cross-linking of actin by bacterial protein toxins -- Common themes in cytoskeletal remodeling by intracellular bacterial effectors -- Viruses that exploit actin-based motility for their replication and spread -- Multiscale view of cytoskeletal mechanoregulation of cell and tissue polarity -- Molecular control of actin dynamics in vivo insights from Drosophila -- From cytoskeleton to gene expression – actin in the nucleus Actin is one of the most abundant proteins and ubiquitously expressed in all eukaryotes. In recent years, the analysis of structure and function of such complexes has shed new light on actin's role in cellular and tissue morphogenesis, locomotion and various forms of intracellular motility, but also on its role in nuclear processes like chromatin architecture and transcription. Progress in understanding these different physiological phenomena, but also in unravelling the basis of actin-based pathophysiological processes has been made by combining video microscopy, molecular biology, genetics and biochemistry. Thus, the current research on actin, as ongoing in many international laboratories, is a "hot spot" in basic and translational research in life sciences. In this book on "The Actin Cytoskeleton", twelve internationally renowned authors present specific chapters that cover their recent work concerned with the various roles of actin mentioned above. This comprehensive volume is therefore an attractive handbook for teachers and students in many fields of medicine and pharmacology Modo de acceso: World Wide Web Medicine Pharmacology Cell physiology Biomedicine Pharmacology/Toxicology Cell Physiology Ciencias biomédicas Libros electrónicos Recursos electrónicos Jockusch, Brigitte M SpringerLink (Online service)