Descripción del título
Gliomas, developing in the brain from the transformed glial cells, are a very special kind of tumors, extremely refractory to conventional treatments. Therefore, for the development of new antitumor strategies, a better understanding of molecular mechanisms responsible for their biology, growth and invasion is still needed. Glioma Signaling is a text reference on cellular signaling processes regulating gliomas physiology and invasiveness. The first half of the book is focused on the mechanism of nucleotide receptor activation by exogenous nucleotides. The remaining chapters deal with the formation of complex signaling cascades, including cytoplasmic transcription factors, induced by growth factors, cytokines and cannabinoids. The book provides a framework explaining how signal transduction elements may modulate glioma cytoskeleton structure, cytoplasmic calcium concentration, cellular growth, progression and invasion, as well as presents perspectives concerning potential targets for glioma therapy
Monografía
monografia Rebiun21681445 https://catalogo.rebiun.org/rebiun/record/Rebiun21681445 cr c||||||||| 120809s2013 ne o 001 0 eng d 9789400747197 978-94-007-4719-7 10.1007/978-94-007-4719-7 doi UEM 76745 UPVA 997152401003706 UAM 991007700893904211 UAL spa UAL rdc MBGR bicssc MED000000 bisacsh 610 23 Glioma Signaling edited by Jolanta Baranska Dordrecht Springer Netherlands Imprint: Springer 2013 Dordrecht Dordrecht Springer Netherlands Imprint: Springer 1 recurso en línea 1 recurso en línea X, 227 p. 39 illus., 27 illus. in color X, 227 p. 39 illus., 27 illus. in color Texto (visual) isbdcontent electrónico isbdmedia Advances in Experimental Medicine and Biology 0065-2598 986 Springer eBooks Gliomas, developing in the brain from the transformed glial cells, are a very special kind of tumors, extremely refractory to conventional treatments. Therefore, for the development of new antitumor strategies, a better understanding of molecular mechanisms responsible for their biology, growth and invasion is still needed. Glioma Signaling is a text reference on cellular signaling processes regulating gliomas physiology and invasiveness. The first half of the book is focused on the mechanism of nucleotide receptor activation by exogenous nucleotides. The remaining chapters deal with the formation of complex signaling cascades, including cytoplasmic transcription factors, induced by growth factors, cytokines and cannabinoids. The book provides a framework explaining how signal transduction elements may modulate glioma cytoskeleton structure, cytoplasmic calcium concentration, cellular growth, progression and invasion, as well as presents perspectives concerning potential targets for glioma therapy Modo de acceso: World Wide Web Medicine Cancer research Molecular biology Neurosciences Biomedicine Biomedicine general Cancer Research Molecular Medicine Libros electrónicos Recursos electrónicos Baranska, Jolanta. editor SpringerLink (Online service) Advances in Experimental Medicine and Biology 0065-2598 986