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cover Glioma Signaling / edited b...
Glioma Signaling
Springer Netherlands 2013

Gliomas, developing in the brain from the transformed glial cells, are a very special kind of tumors, extremely refractory to conventional treatments. Therefore, for the development of new antitumor strategies, a better understanding of molecular mechanisms responsible for their biology, growth and invasion is still needed. Glioma Signaling is a text reference on cellular signaling processes regulating gliomas physiology and invasiveness. The first half of the book is focused on the mechanism of nucleotide receptor activation by exogenous nucleotides. The remaining chapters deal with the formation of complex signaling cascades, including cytoplasmic transcription factors, induced by growth factors, cytokines and cannabinoids. The book provides a framework explaining how signal transduction elements may modulate glioma cytoskeleton structure, cytoplasmic calcium concentration, cellular growth, progression and invasion, as well as presents perspectives concerning potential targets for glioma therapy

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Título:
Glioma Signaling / edited by Jolanta Baranska
Editorial:
Dordrecht : Springer Netherlands : Imprint: Springer, 2013
Descripción física:
1 recurso en línea
X, 227 p. 39 illus., 27 illus. in color
Mención de serie:
Advances in Experimental Medicine and Biology, 0065-2598 ; 986
Springer eBooks
Detalles del sistema:
Modo de acceso: World Wide Web
ISBN:
9789400747197 978-94-007-4719-7
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SpringerLink (Online service)
Punto acceso adicional serie-Título:
Advances in Experimental Medicine and Biology, 0065-2598 ; 986

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