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Bio-assays for oxidative st...
This work contains over thirty chapters by leading researchers in the field of oxidative biology, originally presented as articles in an extended Forum in the highly-cited journal, Free Radical Biology & Medicine. The papers in this Forum (or Symposium-in-print) spanned seven issues of the journal, over many months. This is the first time that all of these expert contributions are presented in one place. Reliable methods for measuring OSS in organisms are essential. These would, amongst other things, offer applications as early warning signals for cancer and heart disease - eventually giving a range of measurable oxidation products best related to any given disease state. Additional observations relevant to OSS include: how much do measures of OSS vary in a group of humans? Does OSS decrease as a result of life-change factors and does it increase with age? With disease? With stress? Can a non-invasive, reliable, reputable measure of OSS be identified? This informative book provides the reader with the latest status of studies into OSS, currently used examples of BOSS, and answers to at least some of the questions posed above
Monografía
monografia Rebiun26016885 https://catalogo.rebiun.org/rebiun/record/Rebiun26016885 m o d cr cnu---unuuu 130411s2001 nyua ob 001 0 eng d 9780080929927 electronic bk.) 0080929923 electronic bk.) 0444509577 9780444509574 AU@ 000050985706 DEBBG BV042303137 UPVA 997185690003706 CBUC 991010400149906709 OPELS eng pn OPELS N$T E7B OCLCF UKDOC OCLCO YDXCP OCLCQ OCLCO OCLCQ OCLCO OCLCQ OCLCO UAB YDX LEAUB OCLCO UKBTH OCLCA MED 067000 bisacsh MED 068000 bisacsh 616.07 22 Bio-assays for oxidative stress status (BOSS) edited by William A. Pryor 1st ed New York Elsevier 2001 New York New York Elsevier 1 online resource (ix, 286 pages) illustrations (some color) 1 online resource (ix, 286 pages) Text txt rdacontent computer c rdamedia online resource cr rdacarrier Includes bibliographical references and indexes Front Cover; Bio-Assays for Oxidative Stress Status (BOSS); Copyright Page; INTRODUCTION TO OXIDATIVE STRESS STATUS (OSS); Table of Contents; CHAPTER 1. OXIDATIVE STRESS STATUS: OSS, BOSS, AND ""WILD BILL"" DONOVAN; REFERENCES; CHAPTER 2. NOVEL HPLC ANALYSIS OF TOCOPHEROLS, TOCOTRIENOLS, AND CHOLESTEROL IN TISSUE; INTRODUCTION; MATERIALS AND METHODS; RESULTS AND DISCUSSION; REFERENCES; ABBREVIATIONS; CHAPTER 3. BASELINE DIENE CONJUGATION IN LDL LIPIDS: AN INDICATOR OF CIRCULATING OXIDIZED LDL; INTRODUCTION; ESTIMATION OF IN VIVO LDL OXIDATION LDL OXIDATION MARKERS, ATHEROSCLEROSIS, AND RISK FACTORSLDL-BDC AS AN INDICATOR OF MILDLY OXIDIZED LDL; PERSPECTIVE: LDL-BDC AS A CLINICAL CHEMICAL ASSAY, AND AS AN INDICATOR OF LDL OXIDATION AND THE RISK OF ATHEROSCLEROSIS; CONCLUSIONS; REFERENCES; ABBREVIATIONS; CHAPTER 4. STABLE MARKERS OF OXIDANT DAMAGE TO PROTEINS AND THEIR APPLICATION IN THE STUDY OF HUMAN DISEASE; INTRODUCTION; FORMATION OF SPECIFIC PROTEIN OXIDATION PRODUCTS; METHODOLOGY FOR THE MEASUREMENT OF SIDE CHAIN OXIDATION PRODUCTS; COMPARISON BETWEEN METHODOLOGIES CONFOUNDING FACTORS IN THE MEASUREMENT OF PROTEIN SIDE-CHAIN OXIDATION PRODUCTSDETECTION OF PROTEIN SIDE-CHAIN OXIDATION PRODUCTS IN HUMANS; REFERENCES; ABBREVIATIONS; CHAPTER 5. MEASUREMENT OF OXIDANT-INDUCED SIGNAL TRANSDUCTION PROTEINS USING CELL IMAGING; INTRODUCTION; EXPERIMENTAL PROCEDURES; DISCUSSION; REFERENCES; ABBREVIATIONS; CHAPTER 6. IN VIVO TOTAL ANTIOXIDANT CAPACITY: COMPARISON OF DIFFERENT ANALYTICAL METHODS; INTRODUCTION; ANTIOXIDANT AND REDUCTANT: SEVERAL CONCEPTS RELATED TO ANTIOXIDANT CAPACITY ASSAYS ANTIOXIDANT CAPACITY ASSAYS INVOLVING OXIDANTS THAT ARE NOT NECESSARILY PRO-OXIDANTSANTIOXIDANT CAPACITY ASSAYS INVOLVING OXIDANTS THAT ARE PRO-OXIDANTS; THE COMPARISON OF ORAC ASSAY WITH OTHER ANTIOXIDANT CAPACITY ASSAYS, PARTICULARLY THE FRAP AND TEAC ASSAYS; PLASMA OR SERUM ANTIOXIDANT CAPACITY AND IN VIVO ANTIOXIDANT STATUS: INTERPRETATION OF DATA; CONCLUSION; REFERENCES; CHAPTER 7. CLINICAL APPLICATION OF BREATH BIOMARKERS OF OXIDATIVE STRESS STATUS; INTRODUCTION; BREATH COLLECTION AND ANALYSIS; CLINICAL APPLICATIONS; CONCLUSIONS; REFERENCES CHAPTER 8. ANALYSIS OF OXIDIZED HEME PROTEINS AND ITS APPLICATION TO MULTIPLE ANTIOXIDANT PROTECTIONANALYSIS OF OXIDIZED HEME PROTEINS; APPLICATION ON HSAP TO LITERATURE SPECTRA OF HEME PROTEINS; HSAP IN MULTIPLE ANTIOXIDANT STUDIES; SUMMARY; REFERENCES; ABBREVIATIONS; CHAPTER 9. OXIDATIVE STRESS STATUS-THE SECOND SET; REFERENCES; CHAPTER 10. MEASUREMENT OF F2-ISOPROSTANES AS AN INDEX OF OXIDATIVE STRESS IN VIVO; BIOCHEMISTRY OF THE FORMATION OF ISOPROSTANES; METHODOLOGY FOR MEASUREMENT OF F2-ISOPROSTANES; FAVORABLE CHARACTERISTICS OF F2-ISOPROSTANES AS A MEASURE OF OXIDATIVE STRESS IN VIVO This work contains over thirty chapters by leading researchers in the field of oxidative biology, originally presented as articles in an extended Forum in the highly-cited journal, Free Radical Biology & Medicine. The papers in this Forum (or Symposium-in-print) spanned seven issues of the journal, over many months. This is the first time that all of these expert contributions are presented in one place. Reliable methods for measuring OSS in organisms are essential. These would, amongst other things, offer applications as early warning signals for cancer and heart disease - eventually giving a range of measurable oxidation products best related to any given disease state. Additional observations relevant to OSS include: how much do measures of OSS vary in a group of humans? Does OSS decrease as a result of life-change factors and does it increase with age? With disease? With stress? Can a non-invasive, reliable, reputable measure of OSS be identified? This informative book provides the reader with the latest status of studies into OSS, currently used examples of BOSS, and answers to at least some of the questions posed above Active oxygen- Pathophysiology Oxidative stress Biochemical markers Oxidative Stress- Collected Works Antioxidants- chemistry- Collected Works Biological Assay- methods- Collected Works Biological Markers- analysis- Collected Works Disease Susceptibility- diagnosis- Collected Works MEDICAL- Pathology. MEDICAL- Pathophysiology. Active oxygen- Pathophysiology. Biochemical markers. Oxidative stress. Collected Work Electronic books Pryor, William A. Print version Bio-assays for oxidative stress status (BOSS). 1st ed. New York : Elsevier, 2001 0444509577 (DLC) 2001055560 (OCoLC)48263787