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Adrenocortical carcinoma : ...
This first edition of the textbook "Adrenocortical Carcinoma: Basic Sciences and Clinical Concepts" provides a concise compilation of relevant data advancing our current understanding of this rare cancer. Chapters are dedicated to various aspects of both the basic biology and the clinical science relating to adrenocortical carcinoma (ACC). Expert clinicians introduce the reader to current state-of-the-art clinical care of patients with ACC. As a considerable body of knowledge on ACC has accumulated over the last decades, expert scientists have authored additional sections that serve as a reference source for the experienced researcher as well as an introduction for the trainee in the laboratory or clinic. Clinical topics span the epidemiology, diagnosis and therapy of ACC. Scientific topics areas span the pathology and pathophysiology of ACC with a special focus on experimental models of adrenocortical tumors and recent advances in the genetic aspects and signaling pathways in ACC. The content of this book was compiled and edited with the intent of facilitating the translation of knowledge into future diagnostic and therapeutic tools that will ultimately improve patient care
Monografía
monografia Rebiun36032919 https://catalogo.rebiun.org/rebiun/record/Rebiun36032919 m o d | cr -n--------- 100804s2010 nyua ob 001 0 eng d 1-282-97100-X 9786612971006 0-387-77236-7 10.1007/978-0-387-77236-3 doi UPVA 996880965903706 UAM 991007699565804211 CBUC 991010403812306709 CBUC 991010403812306709 MiAaPQ eng rda pn MiAaPQ MiAaPQ eng MJCL bicssc MED062000 bisacsh 616.9944 Adrenocortical carcinoma basic science and clinical concept Gary D. Hammer, Tobias Else, editors 1st ed. 2011 New York Springer 2010 New York New York Springer 1 online resource (532 p.) 1 online resource (532 p.) Text txt computer c online resource cr Description based upon print version of record Includes bibliographical references and index Preface; Contents; Contributors; Part I History of Adrenocortical Carcinoma Research and Clinical Care; 1 The History of Adrenocortical Carcinoma Treatment A Medical Perspective; 2 The History of Adrenocortical Carcinoma Treatment A Surgical Perspective; Part II Epidemiology, Presentation and Diagnosis; 3 Epidemiology of Adrenocortical Carcinoma; 4 Clinical Presentation and Initial Diagnosis; 5 Diagnostic Approach to Incidentaloma; Part III Imaging; 6 Computed Tomography/Magnetic Resonance Imaging of Adrenocortical Carcinoma; 7 Functional Imaging of Adrenocortical Carcinoma; Part IV Pathology 8 Classical Histopathology and Immunohistochemistry9 Cellular and Molecular Pathology of Adrenocortical Carcinoma; Part V Genetic and Molecular Aspects; 10 Overview of Genetic Syndromes Associated with Adrenocortical Cancer; 11 LiFraumeni Syndrome; 12 TP53 Molecular Genetics; 13 Telomeres and Telomerase in Adrenocortical Carcinoma; 14 Beckwith--Wiedemann Syndrome; 15 The Insulin-Like Growth Factor System in Adrenocortical Growth Control and Carcinogenesis; 16 WNT/-Catenin Signaling in Adrenocortical Carcinoma; Part VI Models of Adrenocortical Cancer 17 Adrenocortical Stem and Progenitor Cells: Implications for Cancer18 Adrenocortical Cell Lines; 19 Mouse Models of Adrenal Tumorigenesis; Part VII Therapies; 20 Overview of Treatment Options for Adrenocortical Carcinoma; 21 Chemotherapy; 22 Mitotane; 23 Pharmacotherapy for Hormone Excess in AdrenocorticalCarcinoma; 24 Surgery for Adrenocortical Carcinoma; 25 Radiation Therapy for Adrenocortical Carcinoma; 26 Follow-Up and Monitoring of Adrenocortical Carcinoma; Part VIII Unique Cohorts and Future Perspectives; 27 Aldosterone-Producing Adrenocortical Carcinoma 28 Adrenocortical Cancer in Children29 Genome-Wide Studies in Adrenocortical Neoplasia; 30 New Strategies for the Treatment of Adrenocortical Carcinoma; Part IX Adrenal Cancer Networks and Registries; 31 The Dutch Adrenal Network; 32 The ENS@T Initiative; Index This first edition of the textbook "Adrenocortical Carcinoma: Basic Sciences and Clinical Concepts" provides a concise compilation of relevant data advancing our current understanding of this rare cancer. Chapters are dedicated to various aspects of both the basic biology and the clinical science relating to adrenocortical carcinoma (ACC). Expert clinicians introduce the reader to current state-of-the-art clinical care of patients with ACC. As a considerable body of knowledge on ACC has accumulated over the last decades, expert scientists have authored additional sections that serve as a reference source for the experienced researcher as well as an introduction for the trainee in the laboratory or clinic. Clinical topics span the epidemiology, diagnosis and therapy of ACC. Scientific topics areas span the pathology and pathophysiology of ACC with a special focus on experimental models of adrenocortical tumors and recent advances in the genetic aspects and signaling pathways in ACC. The content of this book was compiled and edited with the intent of facilitating the translation of knowledge into future diagnostic and therapeutic tools that will ultimately improve patient care English Adrenal glands- Diseases Adrenal glands- Tumors Hammer, Gary D. Else, Tobias 1-4899-8262-0 0-387-77235-9