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High-throughput screening m...

High-throughput screening methods in toxicity testing

Steinberg, Pablo

Wiley 2013

"High-throughput assays are part of a paradigm shift, to more cost-effective and reliable methods, in the testing of chemical and drug safety. This book covers methods, data generation, data analysis, and applications in risk assessment for major toxicological assays to help toxicologists apply and understand the benefits and limits of high-throughput testing assays. Each chapter describes method principles and includes detailed information on data generation, data analysis, and applications in risk assessment. The topic is especially timely given Europe's REACH legislation and the US National Research Council"--

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High throughput screening (Drug development) Toxicity testing

Monografía

monografia Rebiun16210791 https://catalogo.rebiun.org/rebiun/record/Rebiun16210791 121024s2013 njuadf sb 001 0 eng d 9781118065631 hardback) 9781118538180 e-book) UPVA 997927002503706 UPCT u314604 CaPaEBR. CaPaEBR. UMA.RE High-throughput screening methods in toxicity testing Recurso electrónico] edited by Pablo Steinberg Hoboken, N.J. Wiley 2013 Hoboken, N.J. Hoboken, N.J. Wiley xv, 552 p., [16] p. of plates ill. (some col.) xv, 552 p., [16] p. of plates E-Libro Includes bibliographical references and index pt. 1. General aspects -- pt. 2. High-throughput assays to assess different cytotoxicity endpoints -- pt. 3. High-throughput assays to assess DNA damage and carcinogenesis -- pt. 4. High-throughput assays to assess reproductive toxicity, cardiotoxicity, and haematotoxicity -- pt. 5. High-throughput assays to assess drug metabolism and receptor-related toxicity "High-throughput assays are part of a paradigm shift, to more cost-effective and reliable methods, in the testing of chemical and drug safety. This book covers methods, data generation, data analysis, and applications in risk assessment for major toxicological assays to help toxicologists apply and understand the benefits and limits of high-throughput testing assays. Each chapter describes method principles and includes detailed information on data generation, data analysis, and applications in risk assessment. The topic is especially timely given Europe's REACH legislation and the US National Research Council"-- Provided by publisher Electronic reproduction. Palo Alto, Calif. ebrary 2013. Available via World Wide Web. Access may be limited to ebrary affiliated libraries Modo de acceso: World Wide Web E-Libro High throughput screening (Drug development) Toxicity testing Steinberg, Pablo E-Libro (Servicio en línea)

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monografia Rebiun16210791 https://catalogo.rebiun.org/rebiun/record/Rebiun16210791 121024s2013 njuadf sb 001 0 eng d 9781118065631 hardback) 9781118538180 e-book) UPVA 997927002503706 UPCT u314604 CaPaEBR. CaPaEBR. UMA.RE High-throughput screening methods in toxicity testing Recurso electrónico] edited by Pablo Steinberg Hoboken, N.J. Wiley 2013 Hoboken, N.J. Hoboken, N.J. Wiley xv, 552 p., [16] p. of plates ill. (some col.) xv, 552 p., [16] p. of plates E-Libro Includes bibliographical references and index pt. 1. General aspects -- pt. 2. High-throughput assays to assess different cytotoxicity endpoints -- pt. 3. High-throughput assays to assess DNA damage and carcinogenesis -- pt. 4. High-throughput assays to assess reproductive toxicity, cardiotoxicity, and haematotoxicity -- pt. 5. High-throughput assays to assess drug metabolism and receptor-related toxicity "High-throughput assays are part of a paradigm shift, to more cost-effective and reliable methods, in the testing of chemical and drug safety. This book covers methods, data generation, data analysis, and applications in risk assessment for major toxicological assays to help toxicologists apply and understand the benefits and limits of high-throughput testing assays. Each chapter describes method principles and includes detailed information on data generation, data analysis, and applications in risk assessment. The topic is especially timely given Europe's REACH legislation and the US National Research Council"-- Provided by publisher Electronic reproduction. Palo Alto, Calif. ebrary 2013. Available via World Wide Web. Access may be limited to ebrary affiliated libraries Modo de acceso: World Wide Web E-Libro High throughput screening (Drug development) Toxicity testing Steinberg, Pablo E-Libro (Servicio en línea)