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The field of non-viral vector research has rapidly progressed since the publication of the first edition. This new edition is expanded to two separate volumes that contain in-depth discussions of different non-viral approaches, including cationic liposomes and polymers, naked DNA and various physical methods of delivery, as well as a comprehensive coverage of the molecular biological designs of the plasmid DNA for reduced toxicity, prolonged expression and tissue or disease specific genes. New developments such as the toxicity of the non-viral vectors and recent advances in nucleic acid therap
Monografía
monografia Rebiun19883377 https://catalogo.rebiun.org/rebiun/record/Rebiun19883377 m o d | cr -n--------- 050714s2005 ne a ob 001 0 eng d 1-280-63315-8 9786610633159 0-08-045613-8 UPVA 997187647703706 CBUC 991010400575406709 CBUC 991013419006206708 CBUC 991010400575406709 UPVA 997187637703706 CBUC 991010400566106709 CBUC 991010400566106709 CBUC 991013419039206708 MiAaPQ MiAaPQ MiAaPQ eng 616.042 Huang, Leaf Non-Viral Vectors for Gene Therapy, Second Edition NON-VIRAL VECTORS FOR GENE THERAPY Non-viral vectors for gene therapy electronic resource] edited by Leaf Huang, Mien-chie Hung, Ernst Wagner Advances in Genetics Advances in Genetics, 54 Advances in Genetics, Volume 54C Nonviral Vectors for Gene Therapy Non-Viral Vectors for Gene Therapy, Second Edition: Part 2 , Volume 54C 2nd ed Amsterdam Boston Elsevier Academic Press c2005 Amsterdam Boston Amsterdam Boston Elsevier Academic Press 1 online resource (398 p.) 1 online resource (398 p.) Text txt computer c online resource cr Advances in genetics 54, pt. 2 Description based upon print version of record Includes bibliographical references and indexes front cover; copyright; table of contents; front matter; Contributors; Preface; body; Section 1: NAKED DNA, OLIGONUCLEOTIDE AND PHYSICAL METHODS; 1 The Mechanism of Naked DNA Uptake and Expression; 2 Targeted Delivery of Therapeutic Oligonucleotides to Pulmonary Circulation; 3 Naked DNA for Liver Gene Transfer; 4 Hydrodynamic Delivery; 5 Electric Pulse-Mediated Gene Delivery to Various Animal Tissues; Section 2: GENE REGULATION; 6 In Vivo Application of RNA Interference: From Functional Genomics to Therapeutics 7 A Novel Gene Expression System: Non- Viral Gene Transfer for Hemophilia as Model Systems8 Site-Specific Integration with phiC31 Integrase for Prolonged Expression of Therapeutic Genes; 9 Sleeping Beauty Transposon-Mediated Gene Therapy for Prolonged Expression; Section 3: ANIMAL MODEL AND CLINICAL STUDY; 10 Cancer-Specific Gene Therapy; 11 DNA Vaccine; 12 Airway Gene Therapy; 13 Non-Viral Vector as Vaccine Carrier; 14 Non-Viral Vectors for Gene Therapy: Clinical Trials in Cardiovascular Disease; index; back matter; Color Plates The field of non-viral vector research has rapidly progressed since the publication of the first edition. This new edition is expanded to two separate volumes that contain in-depth discussions of different non-viral approaches, including cationic liposomes and polymers, naked DNA and various physical methods of delivery, as well as a comprehensive coverage of the molecular biological designs of the plasmid DNA for reduced toxicity, prolonged expression and tissue or disease specific genes. New developments such as the toxicity of the non-viral vectors and recent advances in nucleic acid therap English Genetic vectors- Therapeutic use Gene therapy Genetic transformation Electronic books Huang, Leaf Hung, Mien-chie Wagner, Ernst 1960-) Nonviral vectors for gene therapy Advances in genetics (CKB)954926956852 (DLC)2011233068 (OCoLC)61765346 0-12-017654-8 Advances in genetics 54, pt. 2