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Deciphering growth / J.-C. ...
Growth is a complex process that is essential to life. Not only does size play an important role in the process of cellular proliferation, but body size is also a critical factor in determining which organisms live longer. In mammals, the major factors involved in the regulation of body growth are known: insulin-like growth factors (IGF) are key regulators of somatic growth. Growth hormone (GH), secreted by the pituitary gland, directly regulates circulating levels of IGF-I, which is the major coordinator of spatio-temporal growth of the organism. In humans, growth involves a number of specific characteristics not found in other species. These include rapid intrauterine growth, deceleration just after birth, a mid-childhood growth spurt, a second deceleration before puberty, an adolescent growth spurt, and finally full statural growth, which is seen somewhat later. The combined knowledge concerning the endocrine and paracrine aspects of growth have led to the introduction of treatment regimens, most effective in GH-deficient children
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monografia Rebiun21580613 https://catalogo.rebiun.org/rebiun/record/Rebiun21580613 m o d cr |n||||||||| 050428s2005 nyua ob 101 0 eng c 2005926672 171129374 262680801 320967033 613457592 647587655 698451199 994778369 1005836120 1035663478 1044143507 1044251076 1044263677 1056299817 1056398988 1056409993 1058090591 1060668996 1077251924 9783540261926 alk. paper) 3540261923 9783540289029 354028902X 6610312923 9786610312924 10.1007/3-540-28902-X doi 978-3-540-26192-6 Springer http://www.springerlink.com COO eng pn COO UAB GW5XE CNTRU YDXCP CEF PUL ITD OCLCQ EBLCP OCLCO MNU E7B IDEBK OCLCQ OCLCF BEDGE OCLCQ DEBSZ NUI OCLCQ OCL OCLCQ OCL CASUM OTZ OCLCQ ESU VT2 STF OCLCQ MUO U3W OCLCQ AU@ OCLCO WYU OCLCA ICG YOU CANPU pcc MFG bicssc MED075000 bisacsh Deciphering growth J.-C. Carel, P.A. Kelly, Y. Christen (eds.). 1st ed New York, NY Springer 2005 New York, NY New York, NY Springer 1 online resource (xiii, 155 pages) illustrations 1 online resource (xiii, 155 pages) Text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Research and perspectives in endocrine interactions Includes bibliographical references and index Evolutionary Trends in Body Size -- Sexual Dimorphism in the Growth of Homo sapiens: Facts, Inferences and Speculation -- Genetic Control of Size at Birth -- The GH/IGF-1 Axis: Insights from Animal Models -- Downstream Mechanisms of Growth Hormone Action -- Growth Hormone Receptor Signaling and Differential Actions in Target Tissues Compared to IGF-I -- IGF-I and Brain Growth: Multifarious Effects on Developing Neural Cells and Mechanisms of Action -- IGF-I Deficiency: Lessons from Human Mutations -- Putting IGF-I Biology into a Clinical Perspective -- IGF Resistance: The Role of the Type 1 IGF Receptor -- The Importance of the National Cooperative Growth Study (NCGS) -- Why we are Treating Children with Growth Hormone: Lessons from the French Registry License restrictions may limit access Growth is a complex process that is essential to life. Not only does size play an important role in the process of cellular proliferation, but body size is also a critical factor in determining which organisms live longer. In mammals, the major factors involved in the regulation of body growth are known: insulin-like growth factors (IGF) are key regulators of somatic growth. Growth hormone (GH), secreted by the pituitary gland, directly regulates circulating levels of IGF-I, which is the major coordinator of spatio-temporal growth of the organism. In humans, growth involves a number of specific characteristics not found in other species. These include rapid intrauterine growth, deceleration just after birth, a mid-childhood growth spurt, a second deceleration before puberty, an adolescent growth spurt, and finally full statural growth, which is seen somewhat later. The combined knowledge concerning the endocrine and paracrine aspects of growth have led to the introduction of treatment regimens, most effective in GH-deficient children English Human growth- Congresses Children- Growth- Congresses Growth Substances- physiology Body Size- physiology Growth- physiology Biomédecine. Sciences de la vie. Children- Growth. Human growth. Electronic books Conference papers and proceedings. Conference papers and proceedings. Carel, J.-C. Jean-Claude) Kelly, Paula Christen, Yves Print version Deciphering growth. 1st ed. New York, NY : Springer, 2005 (DLC) 2005926672 Research and perspectives in endocrine interactions