Descripción del título
Inflammatory Disorders [edi...
The mechanistic basis of chronic inflammation remains unclear. The research sheds new light on the immune cells expressing the activation markers HLA-DR and regulatory T cells (Tregs) and the cells expressing Siglec receptors as being key players in the immune system responsiveness to antigens and thus in lung tissue damage of chronic inflammation. The results help understand the mechanisms of action of common drugs used in COPD, such as formoterol, tiotropium, or corticosteroids, and point to novel drug targets. The chapters also deal with brain damaging effects, by far unrecognized, of inhaled corticosteroid therapy, a time-proven management of chronic inflammatory airway conditions; asthma being a case in point. Novel methods, likely less producing side effects, of macrolide antibiotics administration by inhalation are discussed, emphasizing not only bacteriostatic but also anti-inflammatory action
Monografía
monografia Rebiun22984135 https://catalogo.rebiun.org/rebiun/record/Rebiun22984135 m o d | cr -n--------- 141122s2015 gw s 00 0 eng d 9783319100128 9783319100135 9783319100111 9783319363721 10.1007/978-3-319-10012-8 doi UMA.RE eng MMG bicssc MED071000 bisacsh 610 613 614.44 615 Inflammatory Disorders Recurso electrónico] edited by Mieczyslaw Pokorski Cham Springer International Publishing 2015 Cham Cham Springer International Publishing Cham Springer International Publishing Imprint: Springer 2015 Cham Cham Springer International Publishing Imprint: Springer X, 67 p. 11 il X, 67 p. 11 il Text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Neuroscience and Respiration 839 Description based upon print version of record Includes bibliographical references at the end of each chapters and index Inhaled Corticosteroids Increase Siglec-5/14 Expression in Sputum Cells of COPD Patients -- Tregs and HLA-DR Expression in Sputum Cells of COPD Patients Treated with Tiotropium and Formoterol -- Inhalation of Macrolides: A Novel Approach to Treatment of Pulmonary Infections -- Influence of Denture Plaque Biofilm on Oral Mucosal Membrane in Patients with Chronic Obstructive Pulmonary Disease -- Biophysical Activity of Animal-Derived Exogenous Surfactants Mixed with Rifampicin -- Organic Changes in the Central Nervous System in Children on Chronic Inhaled Corticosteroid Therapy -- Stem Cell Experiments Moves into Clinic: New Hope for Children with Bronchopulmonary Dysplasia -- Soluble Ligand CD40 and Uric Acid as Markers of Atheromatosis in Patients with Obstructive Sleep Apnea -- Carotid Artery Intima-Media Thickness in Hypertensive Patients with Obstructive Sleep Apnea The mechanistic basis of chronic inflammation remains unclear. The research sheds new light on the immune cells expressing the activation markers HLA-DR and regulatory T cells (Tregs) and the cells expressing Siglec receptors as being key players in the immune system responsiveness to antigens and thus in lung tissue damage of chronic inflammation. The results help understand the mechanisms of action of common drugs used in COPD, such as formoterol, tiotropium, or corticosteroids, and point to novel drug targets. The chapters also deal with brain damaging effects, by far unrecognized, of inhaled corticosteroid therapy, a time-proven management of chronic inflammatory airway conditions; asthma being a case in point. Novel methods, likely less producing side effects, of macrolide antibiotics administration by inhalation are discussed, emphasizing not only bacteriostatic but also anti-inflammatory action English Toxicology Family medicine Medicine Pneumology Pharmacology/Toxicology. General Practice / Family Medicine. Health Promotion and Disease Prevention. Pneumology/Respiratory System. Toxicology Family medicine Medicine Pneumology Pharmacology/Toxicology General Practice / Family Medicine Health Promotion and Disease Prevention Pneumology/Respiratory System Pokorski, Mieczyslaw ed. lit 3-319-10011-4 Neuroscience and Respiration 839