Descripción del título
With a focus on practical applications of biophysical techniques, Biophysical Methods for Biotherapeutics helps formulation and analytical scientists in pharma and biotech better understand and use biophysical methods. Author Tapan K. Das links fundamental biophysics to the process of biopharmaceutical development using a chapter organization according to the steps of the drug development process. The text provides information to help organizations develop short- and long-term strategies for resource investment in biophysical research
Monografía
monografia Rebiun27336130 https://catalogo.rebiun.org/rebiun/record/Rebiun27336130 m o d cr ||||||||||| 130923s2014 nju ob 001 0 eng 2013038702 878139188 911602955 961594325 962634549 1055360419 1081211248 1100462785 1101725989 1124483738 1148118338 1244449473 9781118354674 pdf) 1118354672 pdf) 9781118354681 epub) 1118354680 epub) 9781118354667 mobi) 1118354664 mobi) 9781118354698 1118354699 0470938439 9780470938430 9780470938430 cloth) DLC eng rda pn DLC YDX IDEBK EBLCP DG1 N$T CUS YDXCP CDX RECBK NLGGC E7B OCLCF INNDH COO OCLCQ DEBBG OCL OCLCO COCUF DG1 CHVBK OCLCO DEBSZ MERER OCLCO MOR LIP OCLCO PIFAG ZCU OCLCO MERUC OCLCO OCLCQ OCLCO OCLCA U3W OCLCA OCLCQ OCLCO STF NRAMU CRU ICG VTS OCLCQ VT2 AU@ OCLCO OCLCQ WYU OCLCO CUY OCLCO OCLCA TKN OCLCQ OCLCO OCLCQ OCLCO DKC OCLCQ UKAHL UX1 OCLCQ OCLCA OCLCQ OCLCA pcc MED 071000 bisacsh 577.3 Q4 Biophysical methods for biotherapeutics discovery and development applications edited by Dr. Tapan K. Das Hoboken, New Jersey Wiley [2014] Hoboken, New Jersey Hoboken, New Jersey Wiley ©2014 1 online resource 1 online resource Text txt rdacontent computer c rdamedia online resource cr rdacarrier Includes bibliographical references and index Biophysical methods applied in early discovery of a biotherapeutic : case study of an EGFR-IGF1R bispecific adnectin / Michael L. Doyle, James W. Bryson, Virginie Lafont, Zheng Lin, Paul E. Morin, Lumelle A. Schneeweis, Aaron P. Yamniuk, and Joseph Yanchunas Jr -- X-ray crystallography for biotherapeutics / Glen Spraggon -- Solubility and early assessment of stability for protein therapeutics / Sheng-Jiun Wu, Gary L. Gilliland and Yiqing Feng -- Biophysical and structural characterization needed prior to proof of concept / Angela W. Blake-Haskins, Yen-Huei Lin, Zhuchun Wu, Melissa D. Perkins, Thomas M. Spitznagel -- Nucleation, aggregation, and conformational distortion / Christopher J. Roberts -- Utilization of chemical labeling and mass spectrometry for the biophysical characterization of biopharmaceuticals / Justin B. Sperry and Lisa M. Jones -- Application of biophysical and high throughput methods in the preformulation of therapeutic proteins? : facts and fictions / Ahmad M. Abdul-Fattah and Hanns-Christian Mahler -- Bioanalytical methods and immunogenicity assays / Bonita Rup, Corinna Krinos-Fiorotti, Boris Gorovits, Hendrik Neubert -- Structures and dynamics of proteins probed by UV resonance raman spectroscopy / Brian S. Leigh, Diana E. Schlamadinger, and Judy E. Kim -- Freezing and drying-induced micro-/nanoheterogeneity in biological solutions / Alptekin Aksan, Vishard Ragoonanan, and Carol Hirschmugl -- Late stage product characterization : applications in formulation, process and manufacturing development / Christine P. Chan and Li Shi -- Biophysical analyses suitable for chemistry, manufacturing and control sections of the biological license application (BLA) / Zahra Shahrokh, Nazila Salamat-Miller, John J. Thomas With a focus on practical applications of biophysical techniques, Biophysical Methods for Biotherapeutics helps formulation and analytical scientists in pharma and biotech better understand and use biophysical methods. Author Tapan K. Das links fundamental biophysics to the process of biopharmaceutical development using a chapter organization according to the steps of the drug development process. The text provides information to help organizations develop short- and long-term strategies for resource investment in biophysical research Biopharmaceutics- Methodology Biopharmaceutics- methods Drug Discovery- methods Technology, Pharmaceutical- methods MEDICAL- Pharmacology. Biopharmaceutics. Livres électroniques Electronic books Methods (Music) Das, Tapan K. editor Print version Biophysical methods for biotherapeutics. Hoboken, New Jersey : Wiley, [2014] 9780470938430 (DLC) 2013038071