Descripción del título
Modelling the Toxicity of N...
In todays nanotechnology and pharmaceutical research, alternative toxicology testing methods are crucial for ethically and commercially sound practice. This book provides practical guidelines on how to develop and validate quantitative nanostructure-toxicity relationship (QNTR) models, which are ideal for rapidly exploring the effects of a large number of variables in complex scenarios. Through contributions by academic, industrial, and governmental experts, Modelling the Toxicity of Nanoparticles delivers clear instruction on these methods and their integration and use in risk assessment. Specific topics include the physico-chemical characteristics of engineered nanoparticles, nanoparticle interactions, in vivo nanoparticle processing, and more. A much-needed practical guide, Modelling the Toxicity of Nanoparticles is a key text for researchers as well as government and industry regulators
Monografía
monografia Rebiun23138591 https://catalogo.rebiun.org/rebiun/record/Rebiun23138591 cr nn 008mamaa 170206s2017 gw s 00 0 eng d 9783319477541 9783319477527 9783319477534 9783319838144 10.1007/978-3-319-47754-1 doi UMA.RE MMG bicssc MED071000 bisacsh 615 23 Modelling the Toxicity of Nanoparticles Recurso electrónico] edited by Lang Tran, Miguel A. Bañares, Robert Rallo Cham Springer International Publishing 2017 Cham Cham Springer International Publishing Cham Springer International Publishing Imprint: Springer 2017 Cham Cham Springer International Publishing Imprint: Springer XVII, 352 p. 102 il., 83 il. col XVII, 352 p. 102 il., 83 il. col Text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Advances in Experimental Medicine and Biology 947 Engineered Nanoparticles Their physico-chemical characteristics and how to measure them -- Measurement -- The Life-Cycle of Engineered Nanoparticles -- From Dose to Response In vivo Nanoparticle Processing and Potential Toxicity -- From Dose to Response Literature review od (Q)SAR Modelling of Nanomaterial Toxicity -- Systems biology to support nanomaterial grouping -- Multiscale modelling of bionano interface -- Biological Surface Adsorption Index of Nanomaterials - Modeling Surface Interactions of Nanomaterials with Biomolecules -- Case study I - An integrated data-driven strategy for safe-by-design nanoparticles: The FP7 MODERN Project -- Case study II - Compilation of Data and Modeling of Nanoparticle Interactions and Toxicity and in the European NanoPUZZLES Project -- Case study III The construction of a nanotoxicity database: the MOD-ENP-TOX experience In todays nanotechnology and pharmaceutical research, alternative toxicology testing methods are crucial for ethically and commercially sound practice. This book provides practical guidelines on how to develop and validate quantitative nanostructure-toxicity relationship (QNTR) models, which are ideal for rapidly exploring the effects of a large number of variables in complex scenarios. Through contributions by academic, industrial, and governmental experts, Modelling the Toxicity of Nanoparticles delivers clear instruction on these methods and their integration and use in risk assessment. Specific topics include the physico-chemical characteristics of engineered nanoparticles, nanoparticle interactions, in vivo nanoparticle processing, and more. A much-needed practical guide, Modelling the Toxicity of Nanoparticles is a key text for researchers as well as government and industry regulators Toxicology Nanotechnology Biological models Pharmacology/Toxicology. Nanotechnology. Systems Biology. Toxicology Nanotechnology Biological models Pharmacology/Toxicology Systems Biology Tran, Lang ed. lit Bañares, Miguel A ed. lit Rallo, Robert ed. lit 3-319-47752-8 Advances in Experimental Medicine and Biology 947