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The Drosophila larval neuromuscular junction (NMJ) has become one of the most powerful model systems to ask key neurobiological questions. This synapse is unparalleled by its accessibility, its simplicity, and the ability to manipulate genes important for synapse development and function. Its synapses have properties shared by many organisms including humans. The vast majority of genes that when mutated cause congenital disorders of the nervous system in humans, are present in the fruit fly genome, and fly models of human disorders are available. Thus, this preparation is a powerful to
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monografia Rebiun19958935 https://catalogo.rebiun.org/rebiun/record/Rebiun19958935 m o d | cr -n--------- 061116s2006 caua ob 001 0 eng d GBA705517 bnb 1-280-75159-2 9786610751594 0-08-046913-2 UPVA 997185999203706 CBUC 991013419042106708 CBUC 991010727545906709 MiAaPQ MiAaPQ MiAaPQ eng 595.774 Budnik, Vivian FLY NEUROMUSCULAR JUNCTION, VOLUME 75 FLY NEUROMUSCULAR JUNCTION: STRUCTURE AND FUNCTION Fly Neuromuscular Junction: Structure and Function Second Edition FLY NEUROMUSCULAR JUNCTION FLY NEUROMUSCULAR JUNCTION, VOLUME 75 : STRUCTURE AND FUNCTION FLY NEUROMUSCULAR JUNCTION : STRUCTURE AND FUNCTION : INTERNATIONAL REVIEW OF NEUROBIOLOGY THE FLY NEUROMUSCULAR JUNCTION THE FLY NEUROMUSCULAR JUNCTION, VOLUME 75 The fly neuromuscular junction electronic resource] structure and function edited by Vivian Budnik International Review of Neurobiology Fly Neuromuscular Junction, The International Review of Neurobiology, Volume 75C The Fly Neuromuscular Junction: Structure and Function Second Edition , Volume 75C 2nd ed. Catalina Ruiz-Can ada San Diego, Calif. London Elsevier/Academic Press c2006 San Diego, Calif. London San Diego, Calif. London Elsevier/Academic Press 1 online resource (421 p.) 1 online resource (421 p.) Text txt computer c online resource cr International review of neurobiology v. 75 Description based upon print version of record Includes bibliographical references and index Cover; Copyright page; Table of contents; Contributors; Preface; Chapter B. Attractant Molecules During Synaptic Target RecognitionC. Repulsive Molecules During Synaptic Target Recognition; VII. Dynamics of the Target Muscle; VIII. Conclusions; Acknowledgment; References; Chapter 2: Development and Structure of Motoneurons; I. Introduction; II. Development of Motoneurons; A. Early Specification Programs; B. Motoneuron Subclasses: Specification of Ventrally Versus Dorsally Projecting Motoneurons; C. Ventrally Projecting Motoneurons; D. Dorsally Projecting Motoneurons; E. Motoneuron Specification Programs Are Conserved F. Specification of Unique Motoneuron IdentitiesG. From Motoneuron Determinants to Axon Trajectories; III. Class-Specific Patterns of Axonal Trajectories; A. Subsets Within the Class of Ventrally Projecting Motoneurons; B. A Hierarchy of Nerve Branching; IV. Dendritic Development; A. Dendrites: Conservation Between Insects and Vertebrates; B. Organization of the Motor System: Coordinated Patterning of Pre-and Postsynaptic Terminals; C. Regulation of Dendritic Patterning; V. Conclusions; Acknowledgment; References; Chapter 3: The Development of The Drosophila Larval Body Wall Muscles I. IntroductionII. Muscle Specification; III. Muscle Identity; IV. Myoblast Fusion; V. Muscle Attachment; VI. Concluding Remarks; Acknowledgment; References; Chapter 4: Organization of the Efferent System and Structure of Neuromuscular Junctions In Drosophila; I. Introduction; II. General Organization of the Efferent System; III. Neuromodulation? The Organization of Type-II and Type-III Terminals; IV. Synaptic Junctions: The Development, Morphology, and Classification of Type-I Terminals; V. Ultrastructure of Neuromuscular Synapses; VI. Conclusions; Acknowledgment; References Chapter 5: Development of Motoneuron Electrical Properties and Motor OutputI. Introduction; II. Development of Electrical Properties in Motoneurons; III. Development of Synaptic Connectivity; IV. Regulation of Membrane Excitability; V. Regulation of Synaptic Connectivity; A. Role of the Cell Adhesion Molecule FasciclinII; B. TGF-beta Retrograde Signaling Strengthens Both Central and Peripheral Synapses; VI. Summary; Acknowledgment; References; Chapter 6: Transmitter Release at the Neuromuscular Junction; I. Introduction; II. Physiological Properties of Transmitter Release III. Experimental Advantages and Limitations of the Fly NMJ The Drosophila larval neuromuscular junction (NMJ) has become one of the most powerful model systems to ask key neurobiological questions. This synapse is unparalleled by its accessibility, its simplicity, and the ability to manipulate genes important for synapse development and function. Its synapses have properties shared by many organisms including humans. The vast majority of genes that when mutated cause congenital disorders of the nervous system in humans, are present in the fruit fly genome, and fly models of human disorders are available. Thus, this preparation is a powerful to English Drosophila melanogaster- Nervous system Fruit-flies- Nervous system Myoneural junction Drosophila melanogaster- Development Fruit-flies- Development Electronic books Budnik, Vivian Ruiz-Cãnada, Catalina Neuromuscular junctions in Drosophila International review of neurobiology (CKB)954926958890 (DLC)2011200620 (OCoLC)61847738 2162-5514 0-12-373613-7 International review of neurobiology v. 75